Another I-595 is located in Broward County, Florida, and runs down the east-west axis of the Fort Lauderdale metropolitan area. It starts on the eastern edge of Fort Lauderdale Hollywood International Airport, as a spur off of US Route 1, and goes north of the airport and south of Port Everglades before crossing Interstate 95 and Florida's Turnpike. At its junction with Interstate 75 and the Sawgrass Expressway, it turns into Alligator Alley, the portion of I-75 that crosses the Everglades. Its total run is 12.86 miles.

595 was originally known as State Road 84, the Everglades Expressway. SR-84 still exists, and straddles 595 for most of its length. There are no direct onramps or offramps to 595 in central Broward: instead, you get on 84, and then get on 595. It's a rather efficient system in theory, although it tends to confuse some slow people (and South Florida is full of those).

Technically speaking, 595 is a spur off of 75, not 95. Why it was named as though it were a spur of 95 is largely a mystery.

Despite the fact that 595 is less than fifteen years old, it is already running at 300 percent of its design capacity, and there have been only minimal efforts to offer mass transit alternatives for east-west commuters. 595 is a centerpiece of Broward's growing pains, and will probably remain that way for years to come.