Exon

"Exon" is also a: user

created by Webster 1913
(thing) by everyone (4.6 mon) (print)   (I like it!) Mon Jun 12 2000 at 3:33:57

A polynucleotide segment of RNA which forms "messenger" RNA and is thus present after splicing. Exons are the portion of RNA that contain what we currently believe to be the useful parts of the genetic code, used for protein synthesis. Compare intron.

(thing) by Gritchka (2.6 y) (print)   (I like it!) Sun Feb 18 2001 at 21:06:15
In some cases exons form distinct subregions of the gene, called domains, and at some points in the editing of the primary transcript there may be a choice of exons. Which one to use is then dependent on environmental conditions in the cell. That is, one gene can make several different proteins.

For example a B cell, a kind of lymphocyte, produces antibodies. Early on in its differentiation it needs to retain them at the cell membrane, but later it needs them to circulate, and it achieves this by switching exons, so that the "same" gene now codes for slightly different proteins.

Apparently the latest Human Genome Project figures show that as much as 60% of our genome may have splice variants like this!

In such cases the exons might have evolved as distinct genes and become permanently associated (having a single promoter site and a single terminator).

However not all exons represent bounded domains. In these cases they are probably single genes whose integrity has been invaded by junk DNA introns. Since introns usually begin and end with characteristic two-base sequences, presumably natural selection has spared intrusive junk that just happens to fit the code for domain boundaries.


About the other senses of the word, given by Webster, an exon is one of four officers commanding the Yeomen of the Royal Guard, styled corporal in their commissions, and ranking below an ensign. The word, dating from 1767, derives from the French pronunciation of 'exempt'.
And Exon. is actually the abbreviation of the Latin name of the city of Exeter, viz Exonia, and of its corresponding adjective Exoniensis.
(idea) by Jargon (2 y) (print)   (I like it!) Thu Jul 19 2001 at 8:18:38
exercise, left as an = E = Exploder

Exon /eks'on/ excl.

A generic obscenity that quickly entered wide use on the Internet and Usenet after Black Thursday. From the last name of Senator James Exon (Democrat-Nebraska), primary author of the CDA.

--The Jargon File version 4.3.1, ed. ESR, autonoded by rescdsk.

(definition) by Webster 1913 (print) Tue Dec 21 1999 at 23:32:37

Ex"on (?), n. [NL., from E. Exe (Celt. uisge water) the name of a river.]

A native or inhabitant of Exeter, in England.

 

© Webster 1913.


Ex"on, n. [F. expect an under officer.]

An officer of the Yeomen of the Guard; an Exempt.

[Eng.]

 

© Webster 1913.

Y'know, if you log in, you can write something here, or contact authors directly on the site. Create a New User if you don't already have an account.