ribosome

created by Elm Tree
(thing) by Elm Tree (1.6 y) (print)   (I like it!) Sat Nov 13 1999 at 14:27:12
An Organelle found in the cytoplasm of a cell. They are the centers of protein synthesis. They accept mRNA and using tRNA translate genes into proteins.
(thing) by fhayashi (6.6 mon) (print)   (I like it!) Mon Jan 15 2001 at 4:36:20

Ribosomes are organelles. It's just not a membrane bound organelle.

Ribosomes are made up of two proteins, and a small chunk of RNA called rRNA, for ribosomal RNA.

(thing) by Gritchka (2.6 y) (print)   (I like it!) 1 C! Sun Feb 18 2001 at 19:42:32
A functioning ribosome comes into existence and starts protein synthesis when the smaller ribosomal subunit, having found some mRNA, combines with the larger ribosomal subunit. The ribosome then begins to move along the mRNA asking for tRNA to transcribe it into the successive amino acids of the protein.

The leading end of the ribosome is called the P-site and the one behind it is the A-site. They attach to adjacent codons on the mRNA. They then wait for specific tRNA molecules having the correct antisense sites for those codons.

tRNA consists of RNA with two arms, one containing an amino acid and the other the antisense codon or anticodon that codes for that amino acid. Once the tRNA is correctly docked, the ribosome uses peptidyl transferase to bind the two amino acids, making a peptide bond.

The P-site one detaches, the A-site one moves along into the P-site, and the A-site is now free to await the next tRNA.

Synthesis is terminated when a stop codon is reached. The RNA stop codons are UAA, UAG, and UGA. The chain of amino acids so constructed then folds the resultant polypeptide into its active protein form.

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