not only does God play dice with the universe, he throws them where they cannot be seen
Stephen Hawking in reference to quantum mechanics and black holes
On the whole Einstein thing, a better translation form the German would be God is slick but he is no malicious. It is about the physics as hramyaegr says, but it was not due to a lack of knowledge surrounding the subject at the time. It was a statement of Einstein's disagreement with the proababilistic nature of quantum mechanics. He held to his point of view, that the world was determanistic and that we didn't have a good enough theory to realise this, right untill his death. By the time of his death quantum mechanics was quite well understood.